Recent Publications from the Department of Emergency Medicine


Beeson MS, Bhat R, Broder JS, Gaeta TJ, Janssen A, Karl ER, Lo BM, Moll J, Oh L, Patel V, Touma L, Barton MA, Keehbauch JN; 2022 EM Model Review Task Force; Melissa A. Barton, M.D.(⁎), and Julia N. Keehbauch(⁎); American Board of Emergency Medicine. The 2022 Model of the Clinical Practice of Emergency Medicine. J Emerg Med. 2023 Mar 28:S0736-4679(23)00063-X. doi: 10.1016/j.jemermed.2023.02.016. Epub ahead of print. PMID: 37244783.


DeMasi SParker MS, Joyce M, Mulligan K, Feeser S, Balderston JR. Thoracic Point‐of‐Care‐Ultrasound is an Accurate Diagnostic Modality for Clinically Significant Traumatic Pneumothorax. Academic Emergency Medicine. 2023, epub ahead of print.  


Mr. Tyler J Harder, Mr. Owen P Leary, Dr. Zhihui Yang, Dr. Brandon Lucke-Wold, Dr. David D Liu, Dr. Megan E.H. Still, Ms. Miao Zhang, Dr. Sharon D Yeatts, Dr. Jason W. Allen, Dr. David Wright, Dr. Derek Merck, and Dr. Lisa H. Merck. Early Signs of Elevated Intracranial Pressure (ICP) on Computed Tomography Correlate with Measured ICP in the Intensive Care Unit and Six-Month Outcome Following Moderate to Severe TBI. Journal of Neurotrauma, J Neurotrauma. 2023 Apr 21.doi: 10.1089/neu.2022.0433.  PMID: 37082956


Heron SL, Calderon Y, Moll J, Rotoli J, Franks N, Hassan M, Ander D, Brown I, Lewis J. Diversity, equity, inclusion, justice-Are we accountable? Acad Emerg Med. 2023 Jan;30(1):70-73. doi: 10.1111/acem.14632. Epub 2022 Dec 12. PMID: 36420622.


Horiuchi YU, Wettersten N, VAN Veldhuisen DJ, Mueller C, Filippatos G, Nowak R, Hogan C, Kontos MC, Cannon CM, Müeller GA, Birkhahn R, Taub P, Vilke GM, McDonald K, Mahon N, Nuñez J, Briguori C, Passino C, Duff S, Maisel A, Murray PT . Galectin-3, Acute Kidney Injury and Myocardial Damage in Patients With Acute Heart Failure. Journal of cardiac failure. 2023 Mar 01; Volume: 29 Issue: 3 Pg: 269 PMID: 36332898 


Horiuchi YU, Wettersten N, Vanveldhuisen DJ, Mueller C, Nowak R, Hogan C, Kontos MC, Cannon CM, Birkhahn R, Vilke GM, Mahon N, Nuñez J, Briguori C, Duff S, Murray PT, Maisel A. The Influence of Body Mass Index on Clinical Interpretation of Established and Novel Biomarkers in Acute Heart Failure. J Card Fail. 2023 Apr 29:S1071-9164(23)00150-1. doi: 10.1016/j.cardfail.2023.03.029. Epub ahead of print. PMID: 37127240.


Lykins V JD, Freedman MT, Zemore Z, Sedhai YR, Lubin S, Sessler CN, Hogan C, Kashiouris MG. Patients Who Decompensate and Trigger Rapid Response Immediately Upon Hospital Admission Have Higher Mortality Than Equivalent Patients Without Rapid Responses. J Patient Saf. 2023 Jun 14. doi: 10.1097/PTS.0000000000001139. Epub ahead of print. PMID: 37310865


Ochalek TA, Ringwood KJ, Davis TT, Gal TS, Wills BK, Sabo RT, Keyser-Marcus L, Martin CE, Polak K, Cumpston KL, Moeller FG.  Rapid induction onto extended-release injectable buprenorphine following opioid overdose: A case series. Drug Alcohol Depend Rep. 2023 Mar 16;7:100144. PMID: 37033158 


Self MD MPH; Matthew S. Shotwell PhD; Kevin W. Gibbs MD; Marjolein de Wit MD; D. Clark Files MD; Michelle Harkins MD; Kristin M. Hudock MD; Lisa H. Merck, MD MPH; Ari Moskowitz MD MPH; Krystle D. Apodaca DNP; Aaron Barksdale MD; Basmah Safdar MD; Ali Javaheri MD; Jeffrey M. Sturek MD PhD; Harry Schrager MD; Nicole Iovine MD PhD; Brian Tiffany MD PhD; Ivor S. Douglas MD; Joseph Levitt MD; LaurenceW. Busse MD; Adit A. Ginde MD MPH; Samuel M. Brown MD; David N. Hager MD PhD; Katherine Boyle MD; Abhijit Duggal MD; Akram Khan MD; Michael Lanspa MD; Peter Chen MD; Michael Puskarich MD; Derek Vonderhaar MD; Lokesh Venkateshaiah MD; Nina Gentile MD; Yves Rosenberg MD; James Troendle PhD; Amanda J. Bistran-Hall BS; Josh DeClercq MS; Robert Lavieri PhD; Meghan Morrison Joly PhD; Michael Orr PhD; Jill Pulley MBA; Todd W. Rice MD; Jonathan S. Schildcrout PhD; Matthew W. Semler MD; LiWang MS; Gordon R. Bernard MD; Sean P. Collins MD; for the ACTIV-4 Host Tissue Investigators. Renin-Angiotensin System Modulation with Synthetic Angiotensin (1-7) and Angiotensin II Type 1 Receptor–Biased Ligand in Adults With COVID-19: Two Randomized Clinical Trials. JAMA. 2023;329(14):1170–1182. doi:10.1001/jama.2023.3546. PUBMED ID 37039791


Wettersten N, Duff S, Horiuchi Y, van Veldhuisen DJ, Mueller C, Filippatos G, Nowak R, Hogan C, Kontos MC, Cannon CM, Müeller GA, Birkhahn R, Taub P, Vilke GM, McDonald K, Mahon N, Nuñez J, Briguori C, Passino C, Maisel A, Murray PT, Ix JH . Implications of worsening renal function before hospitalization for acute heart failure. ESC heart failure. 2023 Feb 01; Volume: 10 Issue: 1 Pg: 532 PMID: 36325747 


Williams GR, Downs JW, Wolf CE, Cumpston KLTobarran NWills BK, Bachmann L. Evaluation of Strontium Interference in Calcium Measurement Procedures and Content in Supplements as Measured by ICP-MS. J Appl Lab Med. 2023 Jan 27;jfac092. doi: 10.1093/jalm/jfac092. Online ahead of print. PMID: 36705074 


Zheng G, He F, Xu J, Hu J, Ge W, Ji X, Wang C, Bradley JL, Peberdy MA, Ornato JP, Jiang L, Toldo S, Wang T, Tang W. The Selective NLRP3-inflammasome inhibitor MCC950 Mitigates Post-resuscitation Myocardial Dysfunction and Improves Survival in a Rat Model of Cardiac Arrest and Resuscitation. Cardiovasc Drugs Ther 2023;37(3):423-433. DOI: 10.1007/s10557-021-07282-z.


Zheng G, Xu J, He F, Hu J, Ge W, Ji X, Wang C, Bradley JL, Peberdy MA, Ornato JP, Toldo S, Wang T, Tang W. Effects of NLRP3 inflammasome blockade on postresuscitation cerebral function in a rat model of cardiopulmonary resuscitation. Biomed Pharmacother 2021;143:112093. DOI: 10.1016/j.biopha.2021.112093.


Balderston JR, Brown CK, Feeser VRGertz ZM. Covert Brain Infarction in Emergency Department Patients: Prevalence, Clinical Correlates, and Treatment Opportunities. Annals of Emergency Medicine. 2022;79:265-9.  


Bernard F MD; Barsan W MD; Diaz-Arrastia R MD PhD; Merck LH MD MPH; Yeatts S PhD; Shutter L MD. Brain Oxygen Optimization in Severe Traumatic Brain Injury (BOOST-3): A multicenter, randomized, blinded-endpoint, comparative effectiveness study of brain tissue oxygen and intracranial pressure monitoring versus intracranial pressure alone. British Medical Journal Open, BMJ Open 2022;12:e060188. doi:10.1136/bmjopen-2021-060188


Dainty KN, Colquitt B, Bhanji F, Hunt EA, Jefkins T, Leary M, Ornato JP, Swor RA, Panchal A. Understanding the Importance of the Lay Responder Experience in Out-of-Hospital Cardiac Arrest: A Scientific Statement From the American Heart Association. Circulation 2022;145(17):e852-e867. DOI: 10.1161/CIR.0000000000001054.


Kirk L Cumpston, Viviana Rodriguez, Tammy T. Nguyen, Adam MacLasco, Carolyn Zin, S Rutherfoord Rose, Jeffrey Ferguson, Brandon K. Wills. Evaluation of prehospital hydroxocobalamin use in the setting of smoke inhalation. American Journal of Emergency Medicine. 2022 Jun. doi: 10.1016/j.ajem.2021.10.002. 34674919


Del Buono B, Salhi B, Kimmel A, Santen S, Jarrell K, White M, Brown C, Moll J. Prioritizing Homelessness in Emergency Medicine Education: A Concept Paper. AEM Educ Train. 2022; 6(Suppl. 1): S85– S92. doi:10.1002/aet2.10753


DeMasi S, Taylor LA, Weltler A, Wiggins JC, Wayman J, Wang C, Evans DPBalderston JR. Novel quality assessment methodology in focused cardiac ultrasound. Academic Emergency Medicine. 2022;29:1261-3. 


Driver L, Egan DJ, Hsiang E, Lall M, Moll J, Ritchie A, Sonn B, Totten V, Williams D, McGregor A. Block by block: Building on our knowledge to better care for LGBTQIA+ patients. AEM Educ Train. 2022; 6(Suppl. 1): S57– S63. doi:10.1002/aet2.10755

Fermann GJ, Schrock JW, Levy PD, Pang P, Butler J, Chang AM, Char D, Diercks D, Han JH, Hiestand B, Hogan C, Jenkins CA, Kampe C, Khan Y, Kumar VA, Lee S, Lindenfeld J, Liu D, Miller KF, Peacock WF, Reilly CM, Robichaux C, Rothman RL, Self WH, Singer AJ, Sterling SA, Storrow AB, Stubblefield WB, Walsh C, Wilburn J, Collins SP . Troponin is unrelated to outcomes in heart failure patients discharged from the emergency department. Journal of the American College of Emergency Physicians open. 2022 Apr 09; Volume: 3 Issue: 2 Pg: e12695 PMID: 35434709


Michael Hasbrouck, Tammy T. Nguyen. Acute management of atrial fibrillation in congestive heart failure with reduced ejection fraction in the emergency department. American Journal of Emergency Medicine. 2022 Aug. doi/10.1016/j.ajem.2022.03.058. PMID: 35623182


He F, Zheng G, Hu J, Ge W, Ji X, Bradley JL, Peberdy MA, Ornato JP, Tang W. Necrosulfonamide improves post-resuscitation myocardial dysfunction via inhibiting pyroptosis and necroptosis in a rat model of cardiac arrest. Eur J Pharmacol 2022;926:175037. DOI: 10.1016/j.ejphar.2022.175037.


Horiuchi Y, Wettersten N, van Veldhuisen DJ, Mueller C, Filippatos G, Nowak R, Hogan C, Kontos MC, Cannon CM, Müeller GA, Birkhahn R, Taub P, Vilke GM, Barnett O, McDonald K, Mahon N, Nuñez J, Briguori C, Passino C, Duff S, Maisel A, Murray PT . Decongestion, kidney injury and prognosis in patients with acute heart failure. International journal of cardiology. 2022 May 01; Volume: 1 Issue: 354 Pg: 29-37 PMID: 35202737 


Horiuchi Y, Wettersten N, Patel MP, Mueller C, Neath SX, Christenson RH, Morgenthaler NG, McCord J, Nowak RM, Vilke GM, Daniels LB, Hollander JE, Apple FS, Cannon CM, Nagurney JT, Schreiber D, deFilippi C, Hogan C, Diercks DB, Headden G, Limkakeng AT Jr, Anand I, Wu AHB, Ebmeyer S, Jaffe AS, Peacock WF, Maisel A . Prognosis is worse with elevated cardiac troponin in nonacute coronary syndrome compared with acute coronary syndrome. Coronary artery disease. 2022 Aug 01; Volume: 33 Issue: 5 Pg: 376-384 PMID: 35880560 


Hsiang E, Lall M, Ritchie A, Driver K, Moll J, Sonn B, Williams D, Totten V, McGregor A, Egan D. Emergency Care of LGBTQIA+ Patients Required more than Deconstructing the Alphabet Soup. AEM Education and Training. AEM Educ Train. 2022; 6(Suppl. 1): S52– S56. doi:10.1002/aet2.10750


Hu Z, Gao S, Yang J, Xu B, Tang W, Bradley JL, Peberdy MA, Ornato JP. Ivabradine-Induced Heart Rate Reduction Increases the Severity of Postresuscitation Myocardial Dysfunction in a Rat Model of Cardiopulmonary Resuscitation. Shock 2022;58(6):573-581. DOI: 10.1097/SHK.0000000000002020.


Jin T, He Q, Cheng C, Li H, Liang L, Zhang G, Su C, Xiao Y, Bradley J, Peberdy MA, Ornato JP, Tang W. UAMC-3203 or/and Deferoxamine Improve Post-Resuscitation Myocardial Dysfunction Through Suppressing Ferroptosis in a Rat Model of Cardiac Arrest. Shock 2022;57(3):344-350. DOI: 10.1097/SHK.0000000000001869.


Kershner ETobarran N, Chambers A, Jenkins ZWills BK, Cumpston KL.  Clinical characteristics and outcomes using dexmedetomidine in nonintubated patients: A poison center observational study. Am J Health Syst Pharm. 2022 Dec 21:zxac378. PMID: 36546397 


Kershner ETobarran N, Chambers AWills BKCumpston KL. Retained bullets and lead toxicity: a systematic review. Clin Toxicol (Phila). 2022 Sep 8:1-11. PMID: 36074021 


Maciel CB, Barlow B, Lucke-Wold B, Gobinathan A, Abu-Mowis Z, Peethala MM, Merck LH, Aspide R, Dickinson K, Miao G, Shan G, Bilotta F, Morris NA, Citerio G, Busl KM. Acute Headache Management for Patients with Subarachnoid Hemorrhage: An International Survey of Health Care Providers. Neurocrit Care. 2022 Aug 2. doi: 10.1007/s12028-022-01571-7. PMID: 35915347.


Joseph R Madsen MD, Mustafa Q Hameed MD, Tehnaz P Boyle MD PhD, Mark I Neuman MD MPH, Eun-Hyoung Park PhD, Mandeep S Tamber MD PhD, Robert W Hickey MD, Gregory G Heuer MD, Joseph Zorc MD MSCE, Jeffery R Leonard MD, Julie C Leonard MD MPH, Robert Keating MD, James Chamberlain MD, David M Frim MD PhD, Paula Zakrzewshi RN MSN, Petra Klinge MD PhD, Lisa H Merck MD MPH, Joseph H Piatt MD, Jonathan E Bennett MD, David I Sandberg MD, Frederick A Boop MD. Non-invasive Thermal Flow Evaluation of Ventriculoperitoneal Shunt Flow Improves Diagnostic Accuracy of Shunt Malfunction: A Prospective, Multi-Site, Operator-Blinded Study. Neurosurgery, nyaa128, Published: 27 May 2020


Shraddha Mainali MD, Danilo Cardim PhD, Aarti Sarwal MD, Lisa H Merck MD MPH, Sharon D Yeatts PhD, Marek Czosnyka PhD, Lori Shutter MD. Prolonged Automated Robotic TCD Monitoring in Acute Severe TBI: Study Design and Rationale. Neurocrit Care (2022), Published 06 April 2022.


Moskowitz A, Shotwell MS, Gibbs KW, Harkins M, Rosenberg Y, Troendle J, Merck LH, Files DC, de Wit M, Hudock K, Thompson BT, Gong MN, Ginde AA, Douin DJ, Brown SM, Rubin E, Joly MM, Wang L, Lindsell CJ, Bernard GR, Semler MW, Collins SP, Self WH; Fourth Accelerating COVID-19 Therapeutic Interventions and Vaccines Host Tissue Investigators. Oxygen-Free Days as an Outcome Measure in Clinical Trials of Therapies for COVID-19 and Other Causes of New-Onset Hypoxemia. Chest. 2022 Apr 30:S0012-3692(22)00889-3. doi: 10.1016/j.chest.2022.04.145. Epub ahead of print. PMID: 35504307; PMCID: PMC9055785.


Nolan JP, Ornato JP, Parr MJA, Perkins GD, Soar J. Resuscitation highlights in 2021. Resuscitation 2022;172:64-73. DOI: 10.1016/j.resuscitation.2022.01.015.


Tammy T. Nguyen, Craig F. Kirkwood, Denise Reilly, Danyae Lee, Christy Coggin. Pet Medications: A Tail of Caution. Journal of Pharmacy Practice. 2022 Apr. doi: 10.1177/0897190020966149. PMID: 33161811.


Ornato JP, Dunbar EG, Harbour W, Ludin T, Peberdy MA. Importance of Analyzing Intervals to Emergency Medical Service Treatments. Prehosp Emerg Care 2022:1-7. DOI: 10.1080/10903127.2022.2107124.


Peacock WF, Soto-Ruiz KM, House SL, Cannon CM, Headden G, Tiffany B, Motov S, MerchantBorna K, Chang AM, Pearson C, Patterson BW, Jones AE, Miller J, Varon J, Bastani A, Clark C, Rafique Z, Kea B, Eppensteiner J, Williams JM, Mahler SA, Driver BE, Hendry P, Quackenbush E, Robinson D, Schrock JW, D'Etienne JP, Hogan CJ, Osborne A, Riviello R, Young S . Utility of COVID-19 antigen testing in the emergency department. Journal of the American College of Emergency Physicians open. 2022 Jan 15; Volume: 3 Issue: 1 Pg: e12605 PMID: 35072154 


Michael A Puskarich MD MS; Nicholas E Ingraham MD; Lisa H Merck MD MPH; Brian E Driver MD; David A Wacker MD PhD; Lauren P Black MD MPH; Alan E Jones MD; Courtney V Fletcher PharmD; Andrew M South MD MS; Thomas A Murray PhD; Christopher Lewandowski MD; Joseph Farhat MD; Justin L Benoit MD MS; Michelle H Biros MD MS; Kartik Cherabuddi MD; Jeffrey G Chipman MD; Timothy W Schacker MD; Faheem W Guirgis MD; Helen T Voelker BA; Joseph S Koopmeiners PhD; Christopher J Tignanelli MD MS; for the Angiotensin Receptor Blocker Based Lung Protective Strategies for Inpatients With COVID-19 (ALPS-IP) Investigators. Efficacy of Losartan in Hospitalized Patients with COVID-19–Induced Lung Injury: A Randomized Clinical Trial. JAMA Netw Open. 2022;5(3):e222735. doi:10.1001/jamanetworkopen.2022.2735.


Radica N, Parlier-Ahmad AB, Wills B, Martin CE. Social determinants of health and emergency department utilization among adults receiving buprenorphine for opioid use disorder. Drug Alcohol Depend Rep. 2022;3:1-5. PMID: 35783992. 


Stein DM, Braverman MA, Phuong J, Shipper E, Price MA, Bixby PJ, Adelson PD, Ansel BM, Cifu DX, DeVine JG, Galvagno SM, Gelb DE, Harris O, Kang CS, Kitagawa RS, McQuillan KA, Patel MB, Robertson CS, Salim A, Shutter L, Valadka AB, Bulger EM, Adelson PD, Ansel BM, Chesnut RM, Cifu DX, DeVine JG, Galvagno SM, Gelb DE, Giacino JT, Harris O, Hawryluk G, Kang CS, Kitagawa RS, Manley GT, McQuillan KA, Merck LH, Okonkwo DO, Patel MB, Robertson CS, Salim A, Shackelford CSA, Sheth KN, Shutter L, Stein DM, Valadka AB, Wade CE, Whyte J; Developing a National Trauma Research Action Plan (NTRAP): Results from the Neurotrauma Research Panel Delphi Survey, and the NTRAP Neurotrauma Panel Group. J Trauma Acute Care Surg. 2022 Jan 6. doi: 10.1097/ TA.0000000000003527. Epub ahead of print. PMID: 35001020.


Su C, Xiao Y, Zhang G, Liang L, Li H, Cheng C, Jin T, Bradley J, Peberdy MA, Ornato JP, Mangino MJ, Tang W. Exogenous Nicotinamide Adenine Dinucleotide Attenuates Postresuscitation Myocardial and Neurologic Dysfunction in a Rat Model of Cardiac Arrest. Crit Care Med 2022;50(2):e189-e198. DOI: 10.1097/CCM.0000000000005268.


Tobarran NKershner E, Chambers A, Cumpston KLWills BK. Systemic toxicity from subcutaneous brimonidine injection successfully treated with naloxone. Am J Emerg Med. 2022 Sep;59:218.e5-218.e6. doi: 10.1016/j.ajem.2022.07.007. Epub 2022 Jul 6. PMID: 35835657 


Vitto CM, Lykins V JD, Wiles-Lafayette H, Aurora TK. Blood Pressure Assessment and Treatment in the Observation Unit. Curr Hypertens Rep. 2022 May 20. PMID: 35596047

Wang C, Bischof E, Xu J, Guo Q, Zheng G, Ge W, Hu J, Georgescu Margarint EL, Bradley JL, Peberdy MA, Ornato JP, Zhu C, Tang W. Effects of Methylprednisolone on Myocardial Function and Microcirculation in Post-resuscitation: A Rat Model. Front Cardiovasc Med 2022;9:894004. DOI: 10.3389/fcvm.2022.894004.


Xiao Y, Su C, Zhang G, Liang L, Jin T, Bradley J, Ornato JP, Tang W. Vitamin C Improves the Outcomes of Cardiopulmonary Resuscitation and Alters Shedding of Syndecan-1 and p38/MAPK Phosphorylation in a Rat Model. J Am Heart Assoc 2022;11(7):e023787. DOI: 10.1161/JAHA.121.023787.


Xu J, Zheng G, Hu J, Ge W, Bradley JL, Ornato JP, Tang W. The monoacylglycerol lipase inhibitor, JZL184, has comparable effects to therapeutic hypothermia, attenuating global cerebral injury in a rat model of cardiac arrest. Biomed Pharmacother 2022;156:113847. DOI: 10.1016/j.biopha.2022.113847.


Balderston JR. Echocardiography during cardiac arrest: Time to incorporate into ACLS? Resuscitation. 2021;169:173-4. 


Balderston JR, You AX, Evans DP, Taylor LAGertz ZM. Feasibility of focused cardiac ultrasound during cardiac arrest in the emergency department. Cardiovascular Ultrasound. 2021;19:1-5. 


Balderston JR, Gertz ZM, Seedat R, Rankin JL, Hayes AW, Rodriguez VA, Golladay GJ. Differential Documentation of Race in the First Line of the History of Present Illness. JAMA Internal Medicine. 2021;181(3):386-8. 


Cheng C, Li H, Liang L, Jin T, Zhang G, Bradley JL, Peberdy MA, Ornato JP, Wijesinghe DS, Tang W. Effects of omega-3 PUFA and ascorbic acid combination on post-resuscitation myocardial function. Biomed Pharmacother 2021;133:110970. DOI: 10.1016/j.biopha.2020.110970.


Guo Q, Yang J, Hu Z, Xiao Y, Wu X, Bradley J, Peberdy MA, Ornato JP, Mangino MJ, Tang W. Polyethylene glycol-20k reduces post-resuscitation cerebral dysfunction in a rat model of cardiac arrest and resuscitation: A potential mechanism. Biomed Pharmacother 2021;139:111646. DOI: 10.1016/j.biopha.2021.111646.


Ji X, Bradley JL, Zheng G, Ge W, Xu J, Hu J, He F, Shabnam R, Peberdy MA, Ornato JP, Chen Q, Lesnefsky EJ, Tang W. Cerebral and myocardial mitochondrial injury differ in a rat model of cardiac arrest and cardiopulmonary resuscitation. Biomed Pharmacother 2021;140:111743. DOI: 10.1016/j.biopha.2021.111743.


FK Korley, V Durkalski-Mauldin, SD Yeatts, K Schulman, RD Davenport, LJ Dumont, N El Kassar, LD Foster, JM Hah, S Jaiswal, A Kaplan, E Lowell, JF McDyer, J Quinn, DJ Triulzi, C Van Huysen, VLW Stevenson, K Yadav, CW Jones, B Kea, A Burnett, JC Reynolds, CF Greineder, NL Haas, DG Beiser, R Silbergleit, W Barsan, and CW Callaway, for the SIREN-C3PO Investigators* Early Convalescent Plasma for High-Risk Outpatients with Covid-19 (C3PO). August 18, 2021, at DOI: 10.1056/NEJMoa2103784.


Liang L, Zhang G, Cheng C, Li H, Jin T, Su C, Xiao Y, Bradley J, Peberdy MA, Ornato JP, Mangino MJ, Tang W. High-resolution respirometry for evaluation of mitochondrial function on brain and heart homogenates in a rat model of cardiac arrest and cardiopulmonary resuscitation. Biomed Pharmacother 2021;142:111935. DOI: 10.1016/j.biopha.2021.111935


Liang L, Zhang G, Li H, Cheng C, Jin T, Su C, Xiao Y, Bradley J, Peberdy MA, Ornato JP, Mangino MJ, Tang W. Combined Therapy With Polyethylene Glycol-20k and MCC950 Preserves Post-Resuscitated Myocardial Function in a Rat Model of Cardiac Arrest and Cardiopulmonary Resuscitation. J Am Heart Assoc 2021;10(9):e019177. DOI: 10.1161/JAHA.120.019177.


Carolina Maciel; Fernanda JP Teixeira; Katie J Dickinson; Jessica C Spana; Lisa H Merck; Alejandro A Rabinstein; Robert C Sergott; Guogen Shan; Guanhong Miao; Charles A Peloquin; Katharina M Busl; Lawrence J Hirsch. Early Vigabatrin Augmenting GABA-ergic Pathways in Post-Anoxic Status Epilepticus (VIGAB-STAT) Phase IIa Clinical Trial Study Protocol. Neurological Research and Practice, Jan 25, 2022 4:4,


Moll J, Vennard D, Noto R, Moran T, Krieger P, Moreno-Walton L, Heron SL. The Prevalence of Lesbian, Gay, Bisexual, and Transgender Health Education and Training in Emergency Medicine Residency Programs: Where are we now? AEM Education and Training. 2021 Apr 1;5(2)


Tammy T. Nguyen, Aaron Surrey, Benjamin Barmaan, Stephen Miller, Allison Oswalt, David Evans, Harinder Dhindsa. Utilization and extravasation of peripheral norepinephrine in the emergency department. American Journal of Emergency Medicine. 2021 Jan. doi: 10.1016/j.ajem.2020.01.014. PMID: 31959524


Nichol G, Zhuang R, Russell R, Holcomb JB, Kudenchuk PJ, Aufderheide TP, Morrison L, Sugarman J, Ornato JP, Callaway CW, Vaillancourt C, Bulger E, Christenson J, Daya MR, Schreiber M, Idris A, Podbielski JM, Sopko G, Wang H, Wade CE, Hoyt D, Weisfeldt ML, May S. Variation in time to notification of enrollment and rates of withdrawal in resuscitation trials conducted under exception from informed consent. Resuscitation 2021;168:160-166. DOI: 10.1016/j.resuscitation.2021.07.039.


Nolan JP, Ornato JP, Parr MJA, Perkins GD, Soar J. Resuscitation highlights in 2020. Resuscitation 2021;162:1-10. DOI: 10.1016/j.resuscitation.2021.01.037.


Ornato JP, Peberdy MA, Siegel CR, Lindfors R, Ludin T, Garrison D. Delay to initiation of out-of-hospital cardiac arrest EMS treatments. Am J Emerg Med 2021;41:60-65. DOI: 10.1016/j.ajem.2020.12.024.


van Laarhoven C, Jorritsma NKN, Balderston JR, Brinjikji W, Björck M, van Herwaarden J, Jan De Borst G. Systemic review of co-prevalence of arterial aneurysms in the vasculature. European Journal of Vascular and Endovascular Surgery. 2021;61:473-483.   


T Yi, I Pan, S Collins, F Chen, R Cueto, B Hsieh, C Hsieh, JL Smith, L Yang, W Liao, L Merck, H Bai, D Merck, "DICOM Image ANalysis and Archive (DIANA): An Open-Source System for Clinical AI Applications”,  Journal of Digital Imaging, 2021 Dec;34(6):1405-1413. doi: 10.1007/s10278-021-00488-5.Epub 2021 Nov 2.


Balderston JR, Sternberg M, Joyce JM, Evans DP, Gertz ZM. Focused Cardiac Ultrasound in Dyspnea of Unclear Etiology in the Emergency Department: Utility of the FLUID Score. Journal of Ultrasound in Medicine 2020;39:2211-2217. 


James M Chamberlain, Jaideep Kapur, Shlomo Shinnar, Jordan Elm, Maija Holsti, Lynn Babcock, Alex Rogers, William Barsan, James Cloyd, Daniel Lowenstein, Thomas P Bleck, Robin Conwit, Caitlyn Meinzer, Hannah Cock, Nathan B Fountain Ellen Underwood, Jason T Connor, Robert Silbergleit, for the Neurological Emergencies Treatment Trials* and the Pediatric Emergency Care Applied Research Network investigators*.  Efficacy of levetiracetam, fosphenytoin, and valproate for established status epilepticus by age group (ESETT): a double-blind, responsive-adaptive, randomized controlled trial. The Lancet, Published Online March 20, 2020 See online/comment  


Daya MR, Leroux BG, Dorian P, Rea TD, Newgard CD, Morrison LJ, Lupton JR, Menegazzi JJ, Ornato JP, Sopko G, Christenson J, Idris A, Mody P, Vilke GM, Herdeman C, Barbic D, Kudenchuk PJ, Resuscitation Outcomes Consortium I. Survival After Intravenous Versus Intraosseous Amiodarone, Lidocaine, or Placebo in Out-of-Hospital Shock-Refractory Cardiac Arrest. Circulation 2020;141(3):188-198. DOI: 10.1161/CIRCULATIONAHA.119.042240.


Ge W, Zheng G, Ji X, He F, Hu J, Bradley JL, Moore CE, Peberdy MA, Ornato JP, Mangino MJ, Tang W. Effects of Polyethylene Glycol-20k on Coronary Perfusion Pressure and Postresuscitation Myocardial and Cerebral Function in a Rat Model of Cardiac Arrest. J Am Heart Assoc 2020;9(3):e014232. DOI: 10.1161/JAHA.119.014232.


Gould K, Miller S, Moll J. An early holiday surprise: cholecystitis wrapped in Takotsubo cardiomyopathy, a case report. Western Journal of Emergency Medicine. Clin Pract Cases Emerg Med. 2020 Mar 2;4(2):137-141.


Hickam G, Santen SA, Cico S, Manthey D, Wolff M, Moll J, Lambert A, Jordan J, Haas M. Rapid Adaptation to Remote Didactics and Learning in GME. AEM Education and Training. 2020 Sept 8 Author Manuscript. 2020 doi:10.1002/aet2.10528


Shruti Jadon BS, Owen P Leary ScB, Ian Pan BS, Tyler J. Harder MSc BA, David W. Wright MD, Lisa H Merck MD MPH, Derek L. Merck PhD. A Comparative Study of 2D Image Segmentation Algorithms for Traumatic Brain Lesions Using CT Data from the ProTECTIII Multicenter Clinical Trial. Proc. SPIE, Medical Imaging 2020. Proceedings Volume 11318, Medical Imaging 2020: Imaging Informatics for Healthcare, Research, and Applications; 113180Q (2020) Event: SPIE Medical Imaging, 2020, Houston, Texas.


Sudha Jayaraman, Jonathan H. DeAntonio, Stefan W. Leichtle, Jinfeng Han, Loren Liebrecht, Daniel Contaifer, Caroline Young, Christopher Chou, Julia Staschen, David Doan, Naren Gajenthra Kumar, Luke Wolfe, Tammy T. Nguyen, Gregory Chenault, Rahul J. Anand, Jonathan D. Bennett, Paula Ferrada, Stephanie Goldberg, Levi D. Procter, Edgar B. Rodas, Alan P. Rossi, James F.Whelan, Ventaka Ramana Feeser, Michael J. Vitto, Beth Broering, Sarah Hobgood, Martin Mangino, Michel Aboutanos, Lorin Bachmann, Dayanjan S. Wijesinghe. Detecting direct oral anticoagulants in trauma patients using liquid  chromatography–mass spectrometry: A novel approach to medication reconciliation. Journal of Trauma Acute Care Surgery. 2020 April.  doi: 10.1097/TA.0000000000002527. PMID: 31688825.


Owen P Leary ScB*, Lisa H Merck MD MPH*, Sharon D Yeatts PhD, Ian Pan MS, David D Liu ScB, Tyler J Harder MS, Stefan Jung ScB, Scott Collins RT(R)(CT), Maria Braileanu MD, Ziya L Gokaslan MD, Jason W Allen MD PhD, David W Wright MD, Derek Merck PhD. Computer-Assisted Measurement of Traumatic Brain Hemorrhage Volume is More Predictive of Functional Outcome and Mortality than Standard ABC/2 Method: An Analysis of CT Imaging Data from the ProTECTIII Trial. Journal of Neurotrauma:; Nov 1, 2020.


Nolan JP, Ornato JP, Parr MJA, Perkins GD, Soar J. Resuscitation highlights in 2019. Resuscitation 2020;148:234-241. DOI: 10.1016/j.resuscitation.2020.02.001


Ornato JP, You AX, McDiarmid G, Keyser-Marcus L, Surrey A, Humble JR, Dukkipati S, Harkrader L, Davis SR, Moyer J, Tidwell D, Peberdy MA. Feasibility of bystander-administered naloxone delivered by drone to opioid overdose victims. Am J Emerg Med 2020;38(9):1787-1791. DOI: 10.1016/j.ajem.2020.05.103.


Sawyer KN, Humbert A, Leroux BG, Nichol G, Kudenchuk PJ, Daya MR, Grunau B, Wang HE, Ornato JP, Rittenberger JC, Aufderheide TP, Wittwer L, Colella MR, Austin M, Kawano T, Egan D, Richmond N, Vithalani VD, Scales D, Baker AJ, Morrison LJ, Vilke GM, Kurz MC, Resuscitation Outcomes C. Relationship Between Duration of Targeted Temperature Management, Ischemic Interval, and Good Functional Outcome From Out-of-Hospital Cardiac Arrest. Crit Care Med 2020;48(3):370-377. DOI: 10.1097/CCM.0000000000004160.


Simpkins AN, Busl KM, Amorim E, Barnett-Tapia C, Cervenka MC, Dhakar MB, Etherton MR, Fung C, Griggs R, Holloway RG, Kelly AG, Khan IR, Lizarraga KJ, Madagan HG, Onweni CL, Mestre H, Rabinstein AA, Rubinos C, Dionisio-Santos DA, Youn TS, Merck LH, Maciel CB; Neurotherapeutics Symposium 2019. Proceedings from the Neurotherapeutics Symposium on Neurological Emergencies: Shaping the Future of Neurocritical Care. Neurocrit Care. 2020 Sep 21. doi: 10.1007/s12028-020-01085-0. Epub ahead of print. PMID: 32959201


Xiao Y, Contaifer D, Huang W, Yang J, Hu Z, Guo Q, Bradley J, Peberdy MA, Ornato JP, Wijesinghe DS, Tang W. Cannabinoid Receptor Agonist WIN55, 212-2 Adjusts Lipid Metabolism in a Rat Model of Cardiac Arrest. Ther Hypothermia Temp Manag 2020;10(4):192-203. DOI: 10.1089/ther.2019.0038.

2019 (select)

Moll J, Krieger P, Heron SL, Joyce C, Moreno-Walton L. Attitudes, Behavior, and Comfort of Emergency Medicine Residents in Caring for LGBT Patients: What do we know? AEM Educ Train. 2019 Jan 21;3(2):129-135


Feeser V, Santen S, Zemore Z, Appelbaum N, Moll J, Aboff B, Hemphill R. Analysis of the Emergency Medicine Clinical Learning Environment. AEM Education and Training. 2019 Jun 20;3(3):286-290


Pierce AE, Moreno-Walton L, Boatright D, Moll J, Hicks M, Druck J, Lopez B, Oral E, Heron SL. Advancing Diversity and Inclusion: An Organized Approach Through a Medical Specialty Academy. AEM Education and Training. 2019 Dec 31;4(Suppl 1):S40-S46