Medical Toxicology

Brandon Wills

Brandon Wills, D.O., FACEP, FACMT
Toxicology Fellowship Director

Graduates of the VCU Medical Toxicology Fellowship Program possess a spectrum of skills that enable them to:

  • Provide comprehensive and skilled consultation for clinical toxicology cases
  • Initiate an independent practice of medical toxicology
  • Integrate into an academic medicine environment
  • Exhibit outstanding teaching skills
  • Manage and provide medical direction for regional poison centers
  • Be successful in research

This two-year fellowship is accredited by the Accreditation Council for Graduate Medical Education.

Division of Clinical Toxicology

Fellows will be directly involved in all aspects of the Division of Clinical Toxicology. We have an active consultation service that evaluates approximately 250 inpatient and 40 outpatient clinic patients annually. There is a diverse patient population ranging from stable to critically ill adults and children with varied complaints, including drug overdose, adverse drug events, envenomations, and occupational and environmental exposures.

Teaching is a major focus of our efforts. Our division runs the medical toxicology clinical rotation that hosts approximately 110 emergency medicine, internal medicine and pediatric residents, as well as medical students, visiting residents and fellows, pharmacy students and pharmacy residents on rotation annually.

As a group, our faculty provides professional education for EMS providers, nurses, medical students, residents and physicians, with at least 150 lectures provided yearly at local, regional and national venues. We also direct toxicology simulation cases in the VCU Medical Centers state-of-the-art simulation center for medical students and residents.

Virginia Poison Center

The Virginia Poison Center External Link annually receives more than 27,000 calls for consultation in human poisonings. The fellow works closely with VPC staff, providing supervised medical consultation in overdose cases.

Fellows will also help provide quality assurance activities as well as participate in the development of poison triage and treatment guidelines for the Specialists in Poison Information. They will have the opportunity to participate in public educational activities.

Research

The Division of Clinical Toxicology and Department of Emergency Medicine are continuously engaging in research and scholarly activities. There are opportunities to collaborate with Ph.D. scientists in the Department of Pharmacology and Toxicology External Link in the School of Medicine as well as the VCU Reanimation Engineering Shock Center External Link.

Publications

The following is a sample of our faculty’s recent publications:

Stromberg, PE and Cumpston KL. Cases from the NACCT acute and intensive care symposium: Altered mental status, seizures, and rash in a fumigation company employee. Clinical Toxicology. 2013; 51(3): 182-185.

Stromberg PE, Wills BK, Rose SR. The Perfect Storm: Colchicine toxicity from Therapeutic Misadventure. Journal of Family Practice. (In press).

Stromberg PE, Montgomery JY, Evans TC, Wills BK. Woman with a hand ulcer. Clinical Toxicology. 2012; 50(3): 222-223.

Matlock A, Allan N, Wills BK, Kang C, Leikin J. A continuing black hole? The FDA boxed warning: An appeal to improve its clinical utility. Clinical Toxicology. 2011; 49(6):443-447.

Wills BK, Bryant S, Buckley P, Seo B. Prevalence of metformin-associated lactic acidosis from acute overdose. Amer J Emerg Med. 2010; 28:857-861.

Jones R, Wills BK, Kang C. Chlorine gas: An evolving hazardous material threat and unconventional weapon. West J Emerg Med. 2010; 11(2):151-156.

Wills BK, Christensen J, Mazzoncini J, Miller M. Severe neurotoxicity following ingestion of tetraethyl lead. J Med Toxicol. 2010 Mar; 6(1):31-4.

Murphy CM, Akbarnia H and Rose SR. Fatal pulmonary edema after acute occupational exposure to nitric acid. J Emerg Med. 2010; 39:39-43.

Stromberg PE, Woolsey CA, Clark AT, Clark JA, Turnbull IR, McConnell KW, Chang KC, Chung CS, Ayala A, Buchman TG, Hotchkiss RS, Coopersmith CM. CD 4+ lymphocytes control gut epithelial apoptosis and mediate survival in sepsis. Federation of American Societies of Experimental Biology Journal. 2009; 23(6): 1817-1825.

Leikin JB, Wills BK. Long-term psychiatric consequences from carbon monoxide exposure: Progression of endogenous cause or toxicant effect? Crit Care Med. 2009; 37(6):2116-8.

Cumpston KL. Regurgitation of my free lunch: The clinical toxicology and pharmaceutical company relationship. J Med Toxicol. 2009 December; 5(4):257.

Beckerman N, Leikin SM, Aitchinson R, Yen M, Wills BK. Laboratory interferences with the newer cyanide antidote-hydroxocobalamin. Semin Diagn Pathol. 2009; 26(1):49-52.

Wills BK, Leikin J, Rhee JW, Tameling C, Saeedi B. Analysis of suspicious powders in Northern Illinois following the post 9/11 anthrax scare. J Med Toxicol. 2008; 4(2):93-95.

Cumpston KL, Aks SE, Sigg T, Pallasch E. Whole bowel irrigation and the hemodynamically unstable calcium channel blocker overdose: Primum non nocere. J Emerg Med. 2008 July.

Wills BK, Aks SE, Maloney GE, Rhee JW, Brand R, Anderson M, Sekosan M. The effect of amifostine, a cytoprotective agent, on paraquatt in mice. J Med Toxicol. 2007; 3(1):1-6.

Whitlow KS, Carmichael JC, Rose SR. Acute poisoning: keys to zeroing in on the cause. Consultant for Pediatricians. 2006; 46:529-34.

Kostic MA, Rose SR, Bebarta VS. Understanding poison control, and protecting its future. Pediatric Annals. 2005; 34:983-988.

Muiz AE, Rose SR, Liner SR, Foster RL. Unsuspected acetaminophen toxicity in a 58 day-old infant. Pediatric Emergency Care. 2004; 20:824-8.

Questions?

For more information on the medical toxicology fellowship program, please contact:

Brandon Wills, D.O., M.S., FACEP, FACMT
Fellowship Director, Medical Toxicology
bwills@mcvh-vcu.edu